INFECTION AND TRANSMISSION OF RIFT VALLEY FEVER VIRUSES LACKING THE NSS AND/OR NSM GENES IN MOSQUITOES: POTENTIAL ROLE FOR NSM IN MOSQUITO INFECTION.

BACKGROUND: Rift Valley fever virus is an arthropod-borne human and animal pathogen responsible for large outbreaks of acute and febrile illness throughout Africa and the Arabian Peninsula.Reverse genetics technology has been used to develop deletion mutants of the virus that lack the NSs and/or NSm virulence genes and have been shown to be stable,

BackgroundSubcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a malignant primary T-cell lymphoma that is challenging to distinguish from autoimmune disorders and reactive panniculitides.Delay in diagnosis and a high misdiagnosis rate affect the prognosis and survival of patients.The difficulty of diagnosis is mainly due to an incomplete unde

Chronic obstructive pulmonary disease (COPD) is a prevalent chronic condition associated with substantial global morbidity and mortality.Primarily caused by prolonged exposure to harmful agents such as dust and gases, COPD is characterized by persistent airflow limitation, clinically manifesting as chronic cough, sputum production, and dyspnea.The

The Smallfin Gulper Shark Centrophorus Pregnancy Tests moluccensis is reported for the first time from the Andaman & Nicobar waters of the Indian EEZ.A male specimen of 785mm total length and weighing 2.34kg was landed by Cargo Shorts a motorized longliner at Burmanallah, South Andaman District.The specimen was caught off Chidiyatapu, South Andaman

MicroRNAs (miRNAs) are a class of noncoding RNAs that negatively regulate target messenger RNAs.In multicellular eukaryotes, numerous miRNAs perform basic cellular functions, including cell proliferation, differentiation, and death.Abnormal expression of miRNAs weakens or modifies various apoptosis pathways, leading to the development of human canc